Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18011080 | 0.80 | MAPT (0.48) | ALDH1A1KDM4ECYP3A4FGFR1SMN1; SMN2 | |
| SCHEMBL715550 | 0.78 | CYP3A4 (0.37) | ALDH1A1KDM4ECYP3A4FGFR1SMN1; SMN2 | |
| SCHEMBL26979909 | 0.76 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDCYP1A2FGFR1 | |
| SCHEMBL28146629 | 0.74 | GRM1 (0.39) | KDM4EMAPT | |
| SCHEMBL24754387 | 0.73 | ALDH1A1 (0.38) | ALDH1A1CYP3A4SMN1; SMN2HTTCYP2C9 | |
| SCHEMBL27250761 | 0.73 | CYP3A4 (0.36) | ALDH1A1KDM4EHPGDCYP1A2BLM | |
| SCHEMBL3561936 | 0.72 | CA12 (0.50) | ALDH1A1KDM4EHPGDCYP1A2BLM | |
| SCHEMBL18011108 | 0.72 | ADRB2 (0.59) | ALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL10059523 | 0.72 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDCYP1A2BLM | |
| SCHEMBL16361758 | 0.71 | SMN1; SMN2 (0.46) | ALDH1A1KDM4EHPGDCYP1A2BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422178-A1 | PYRIMIDINE DERIVATIVES. | ICI PLC (GB) | 1991-04-17 | — | — | EP | disclosed |
| US-4065463-A | Herbicidal 2-methyl-4-phenyl-5-isoxazolinones | ELI LILLY AND COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4000155-A | PREEMERGENCE HERBICIDES | ELI LILLY AND COMPANY (US) | 1976-12-28 | — | — | US | disclosed |