Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL715549 | 0.79 | CYP3A4 (0.41) | CYP3A4CYP2C9IDO1KMT2AALDH1A1 | |
| SCHEMBL9827675 | 0.78 | ALDH1A1 (0.46) | CYP3A4CYP2C9KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL26979909 | 0.78 | ALDH1A1 (0.50) | ALDH1A1HTTKDM4EFGFR1 | |
| SCHEMBL25138280 | 0.70 | IDO1 (0.64) | CYP3A4IDO1KMT2AMEN1 | |
| SCHEMBL18011080 | 0.68 | MAPT (0.48) | CYP3A4CYP2C9KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL13263859 | 0.68 | IDH1 (0.45) | CYP3A4CYP2C9ALDH1A1HTTKDM4E | |
| SCHEMBL22572762 | 0.66 | CRBN (0.65) | ALDH1A1SMN1; SMN2HTTKDM4EHCAR1 | |
| SCHEMBL27250761 | 0.66 | CYP3A4 (0.36) | CYP3A4CYP2C9ALDH1A1KDM4EFGFR1 | |
| SCHEMBL5703372 | 0.65 | GABRG2 (0.44) | CYP2C9IDO1KMT2ASMN1; SMN2HTT | |
| SCHEMBL31512195 | 0.65 | ACLY (0.35) | CYP3A4IDO1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140221201-A1 | INSECTICIDAL ACTIVE MIXTURES COMPRISING ARYLQUINAZOLINONE COMPOUNDS | BASF SE (DE) | 2014-08-07 | — | — | US | disclosed |
| US-20140213445-A1 | Use of Pesticidal Active 3-Arylquinazolin-4-One Derivatives in Soil Application Methods | BASF SE (DE) | 2014-07-31 | — | — | US | disclosed |
| EP-2750503-A1 | INSECTICIDAL ACTIVE MIXTURES COMPRISING ARYLQUINAZOLINONE COMPOUNDS | BASF SE (DE) | 2014-07-09 | — | — | EP | disclosed |
| EP-2750506-A2 | USE OF PESTICIDAL ACTIVE 3-ARYLQUINAZOLIN-4-ONE DERIVATIVES IN SOIL APPLICATION METHODS | BASF SE (DE) | 2014-07-09 | — | — | EP | disclosed |
| EP-2750507-A2 | AGRICULTURAL MIXTURES COMPRISING ARYLQUINAZOLINONE COMPOUNDS | BASF SE (DE) | 2014-07-09 | — | — | EP | disclosed |
| US-8765774-B2 | 3-arylquinazolin-4-one compounds for combating invertebrate pests | BASF SE (DE) | 2014-07-01 | — | — | US | disclosed |
| EP-2403837-B1 | 3-ARYLQUINAZOLIN-4-ONE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2013-12-11 | — | — | EP | disclosed |
| WO-2013030338-A2 | AGRICULTURAL MIXTURES COMPRISING ARYLQUINAZOLINONE COMPOUNDS | BASF SE (DE) | 2013-03-07 | — | — | WO | disclosed |
| WO-2013030319-A2 | USE OF PESTICIDAL ACTIVE 3-ARYLQUINAZOLIN-4-ONE DERIVATIVES IN SOIL APPLICATION METHODS | BASF SE (DE) | 2013-03-07 | — | — | WO | disclosed |
| WO-2013030262-A1 | INSECTICIDAL ACTIVE MIXTURES COMPRISING ARYLQUINAZOLINONE COMPOUNDS | BASF SE (DE) | 2013-03-07 | — | — | WO | disclosed |
| US-20120053052-A1 | 3-Arylquinazolin-4-one compounds for combating invertebrate pests | BASF SE (DE) | 2012-03-01 | — | — | US | disclosed |
| EP-2403837-A1 | 3-ARYLQUINAZOLIN-4-ONE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2012-01-11 | — | — | EP | disclosed |
| WO-2010100189-A1 | 3-ARYLQUINAZOLIN-4-ONE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2010-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221201-A1 | INSECTICIDAL ACTIVE MIXTURES COMPRISING ARYLQUINAZOLINONE COMPOUNDS | MCU, AGK, NLN | CYP3A4 1014/4885CYP2C9 1427/4885IDO1 1505/4885 |
| US-20140213445-A1 | Use of Pesticidal Active 3-Arylquinazolin-4-One Derivatives in Soil Application Methods | DDT, TYR, DPYSL3 | CYP3A4 1719/4885CYP2C9 766/4885IDO1 42/4885 |
| US-20120053052-A1 | 3-Arylquinazolin-4-one compounds for combating invertebrate pests | CBR3, CNPY3, RTN3 | CYP3A4 1338/4885CYP2C9 2141/4885IDO1 990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.