Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9827817 | 0.82 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1NPC1KMT2AMEN1 | |
| SCHEMBL9827239 | 0.78 | ALDH1A1 (0.40) | SMN1; SMN2ALDH1A1NPC1KMT2AMEN1 | |
| SCHEMBL8655123 | 0.74 | CA1 (0.33) | KMT2AMEN1 | |
| SCHEMBL17547305 | 0.70 | — | — | |
| SCHEMBL3148442 | 0.69 | — | — | |
| SCHEMBL9479129 | 0.66 | — | — | |
| SCHEMBL9827215 | 0.65 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1NPC1KMT2AMEN1 | |
| SCHEMBL8346166 | 0.64 | TSHR (0.35) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL11235845 | 0.64 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1NPC1KMT2AMEN1 | |
| SCHEMBL9827332 | 0.63 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1NPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301613-B1 | THIAZOLE COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1991-07-10 | — | — | EP | disclosed |
| US-4889863-A | NONPHYTOTOXIC; SEEDS, SOILS | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1989-12-26 | — | — | US | disclosed |
| EP-0301613-A1 | Thiazole compounds having fungicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1989-02-01 | — | — | EP | disclosed |