SCHEMBL8346166

SCHEMBL8346166

Cc1nc(S(C)(=O)=O)sc1Cl

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
KMT2A Q03164 3/20 0.33
MEN1 O00255 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
CA5A P35218 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8655123 0.80 CA1 (0.33) TSHRKMT2AMEN1CA1CA2
SCHEMBL113995 0.77 NOS1 (0.41) TSHRKMT2ACA1CA2CA4
SCHEMBL11707447 0.66 MEN1 (0.49) KMT2AMEN1ALDH1A1HPGD
SCHEMBL13096082 0.66 PTGDR2 (0.37) KMT2AMEN1ALDH1A1
SCHEMBL3375995 0.66
SCHEMBL2611831 0.66
SCHEMBL16486114 0.65 TSHR (0.35) TSHRKMT2ACA1CA2CA4
SCHEMBL9827775 0.64 SMN1; SMN2 (0.43) KMT2AMEN1ALDH1A1
SCHEMBL22865268 0.64
SCHEMBL9508988 0.64 CA1 (0.47) CA1CA2CA4CA5ACA5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999011129-A1 ENANTIOMERICALLY ENRICHED COMPOSITIONS AND THEIR PESTICIDAL USE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-03-11 WO disclosed