Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829765 | 0.69 | OPRM1 (0.36) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL8488806 | 0.67 | PDK2 (0.37) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL29805110 | 0.67 | PDCD1 (0.39) | — | |
| SCHEMBL5308753 | 0.67 | PDCD1 (0.39) | — | |
| SCHEMBL10152492 | 0.64 | SRC (0.37) | DRD2 | |
| SCHEMBL4964190 | 0.63 | OPRM1 (0.38) | OPRM1OPRD1OPRK1OPRL1HTR2A | |
| SCHEMBL30408176 | 0.62 | OPRL1 (0.50) | OPRM1OPRD1OPRK1OPRL1PDK2 | |
| SCHEMBL744812 | 0.62 | OPRL1 (0.50) | OPRM1OPRD1OPRK1OPRL1PDK2 | |
| SCHEMBL30487798 | 0.62 | SRC (0.49) | — | |
| SCHEMBL31273412 | 0.60 | DRD2 (0.36) | DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239129-B1 | HYDROQUINOLINE COMPOUNDS, COMPOSITIONS CONTAINING SAME AND PROCESSES FOR PREPARING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-25 | — | — | EP | disclosed |
| US-4963566-A | ANTIULCER AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-16 | — | — | US | disclosed |
| EP-0239129-A2 | Hydroquinoline compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-09-30 | — | — | EP | disclosed |