Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3079489 | 0.76 | PDK2 (0.44) | PDK2PGR | |
| SCHEMBL17397785 | 0.73 | PDE7A (0.39) | PDK2 | |
| SCHEMBL3823831 | 0.73 | PDE7A (0.38) | PDK2 | |
| SCHEMBL11934149 | 0.71 | CA2 (0.38) | — | |
| SCHEMBL10828059 | 0.70 | PDK2 (0.38) | PDK2 | |
| SCHEMBL9827965 | 0.67 | OPRM1 (0.33) | PDK2DRD2HTR2AOPRM1OPRD1 | |
| SCHEMBL31273412 | 0.65 | DRD2 (0.36) | DRD2HTR2A | |
| SCHEMBL1031209 | 0.63 | PDK2 (0.42) | PDK2HTR2AOPRM1OPRL1 | |
| SCHEMBL29384370 | 0.63 | PDK2 (0.42) | PDK2HTR2AOPRM1OPRL1 | |
| SCHEMBL7034736 | 0.63 | GSK3B (0.35) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1707202-A1 | Organic compounds | Speedel Experimenta AG (CH) | 2006-10-04 | — | — | EP | disclosed |