SCHEMBL6750273

SCHEMBL6750273

COc1ccc(COC(=O)NCCN)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.58
KMT2A Q03164 4/20 0.58
GLA P06280 1/20 0.58
MAPT P10636 3/20 0.51
ATM Q13315 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
MIF P14174 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.49
HTT P42858 3/20 0.49
LMNA P02545 1/20 0.48
GAA P10253 2/20 0.47
MEN1 O00255 1/20 0.47
MMP1 P03956 1/20 0.47
MMP9 P14780 1/20 0.47
PRSS1 P07477 1/20 0.47
TPSAB1 Q15661 1/20 0.47
TPSD1 Q9BZJ3 1/20 0.47
TPSG1 Q9NRR2 1/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7270508 0.86 SMN1; SMN2 (0.58) ALDH1A1KMT2AGLAMAPTATM
SCHEMBL11526146 0.86 ALDH1A1 (0.60) ALDH1A1KMT2AGLAMAPTATM
SCHEMBL8439121 0.85 ALDH1A1 (0.58) ALDH1A1KMT2AGLAMAPTATM
SCHEMBL9828159 0.84 HTT (0.58) ALDH1A1KMT2AGLAMAPTATM
SCHEMBL29132331 0.82 L3MBTL1 (0.46) ALDH1A1KMT2AGLAMAPTL3MBTL1
SCHEMBL17448403 0.82 SMN1; SMN2 (0.48) KMT2AMAPTL3MBTL1SMN1; SMN2HTT
SCHEMBL11264154 0.81 ALDH1A1 (0.61) ALDH1A1KMT2AGLAMAPTATM
SCHEMBL10924887 0.81 GLA (0.70) ALDH1A1KMT2AGLASMN1; SMN2LMNA
SCHEMBL7009466 0.81 HTT (0.72) ALDH1A1KMT2AGLAMAPTATM
SCHEMBL8737718 0.81 NPC1 (0.72) KMT2AGLAMAPTATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0983290-B1 METHOD FOR PRODUCING POLYMERS HAVING NUCLEO-BASES AS SIDE-GROUPS MORPHOCHEM AG (DE) 2004-03-03 EP disclosed
US-6355726-B1 MULTICOMPONENT UGI REACTION; ANTISENSE AGENTS, ANTIGENS; DIAGNOSIS; CONTROLLING GENE EXPRESSION BY POLYMERIC PEPTIDE NUCLEIC ACIDS MORPHOCHEM AG (DE) 2002-03-12 US disclosed
EP-0983290-A1 METHOD FOR PRODUCING POLYMERS HAVING NUCLEO-BASES AS SIDE-GROUPS Morphochem AG (DE) 2000-03-08 EP disclosed
WO-1998051697-A2 METHOD FOR PRODUCING POLYMERS HAVING NUCLEO-BASES AS SIDE-GROUPS MORPHOCHEM AG (DE) 1998-11-19 WO disclosed