Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831626 | 0.90 | RAB9A (0.36) | RAB9AADAMTS5CYP2C19CYP2C9RXFP1 | |
| SCHEMBL10672763 | 0.88 | ALOX15 (0.35) | RAB9AADAMTS5RXFP1ALDH1A1MAPT | |
| SCHEMBL10672529 | 0.87 | ALOX15 (0.35) | RAB9AADAMTS5RXFP1ALDH1A1MAPT | |
| SCHEMBL9831349 | 0.85 | ADAMTS5 (0.34) | RAB9AADAMTS5RXFP1ALDH1A1MAPT | |
| SCHEMBL10675415 | 0.85 | ALOX15 (0.36) | RAB9AADAMTS5RXFP1ALDH1A1MAPT | |
| SCHEMBL9829878 | 0.83 | KDM4E (0.35) | RAB9ARXFP1ALDH1A1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL9829155 | 0.81 | SMPD1 (0.50) | ALOX15 | |
| Hydrochloric Acid SCHEMBL9829515 | 0.81 | KMT2A (0.40) | CYP2C9MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL9829867 | 0.81 | NQO2 (0.36) | RAB9AADAMTS5RXFP1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL9831407 | 0.80 | SMPD1 (0.51) | ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233291-B1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1991-03-13 | — | — | EP | disclosed |
| US-4739050-A | CALCIUM ANTAGONIST, ANTICOAGULANT | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| EP-0233291-A1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1987-08-26 | — | — | EP | disclosed |