SCHEMBL9828526

SCHEMBL9828526

COc1ccc(OCCCCN(C)CCc2cc(OC)c(OC)c(OC)c2)c(C2(SC)Sc3ccccc3N(C)C2=O)c1

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 11/20 0.42
ABCB1 P08183 1/20 0.36
BCHE P06276 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9829234 0.99 SMPD1 (0.41) SMPD1ABCB1BCHE
Hydrochloric Acid SCHEMBL9831196 0.93 SMPD1 (0.49) SMPD1ABCB1
SCHEMBL9829147 0.91 SMPD1 (0.51) SMPD1ABCB1
Hydrochloric Acid SCHEMBL9832211 0.90 SMPD1 (0.50) SMPD1ABCB1
Hydrochloric Acid SCHEMBL9828653 0.86 BCHE (0.36) SMPD1BCHE
SCHEMBL9829599 0.82 SMPD1 (0.51) SMPD1ABCB1
SCHEMBL9831349 0.82 ADAMTS5 (0.34)
SCHEMBL9829352 0.82 SMPD1 (0.45) SMPD1ABCB1
SCHEMBL9829551 0.82 PTPN1 (0.35)
Hydrochloric Acid SCHEMBL9830009 0.82 SMPD1 (0.51) SMPD1ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0233291-B1 2-ARYLBENZOTHIAZINE DERIVATIVES SANTEN PHARMACEUTICAL CO., LTD. (JP) 1991-03-13 EP claimed
US-4739050-A CALCIUM ANTAGONIST, ANTICOAGULANT SANTEN PHARMACEUTICAL CO., LTD. (JP) 1988-04-19 US claimed
EP-0233291-A1 2-ARYLBENZOTHIAZINE DERIVATIVES SANTEN PHARMACEUTICAL CO., LTD. (JP) 1987-08-26 EP claimed
EP-0096214-B1 ANTIBACTERIAL PYRIMIDINE COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1991-02-27 EP disclosed
US-4587341-A BACTERICIDES BURROUGHS WELLCOME CO. (US) 1986-05-06 US disclosed
EP-0096214-A1 Antibacterial pyrimidine compounds THE WELLCOME FOUNDATION LIMITED (GB) 1983-12-21 EP disclosed