Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.73 |
| ▸ | CNR1 | P21554 | 1/20 | 0.73 |
| ▸ | CNR2 | P34972 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831383 | 1.00 | FAAH (0.73) | FAAHCNR1CNR2ALDH1A1MAPT | |
| SCHEMBL9828555 | 1.00 | FAAH (0.73) | FAAHCNR1CNR2ALDH1A1MAPT | |
| SCHEMBL709383 | 0.84 | FAAH (1.00) | FAAHCNR1CNR2ALDH1A1MAPT | |
| SCHEMBL28213215 | 0.84 | FAAH (0.62) | FAAHCNR1CNR2ALDH1A1MAPT | |
| SCHEMBL5862453 | 0.84 | FAAH (0.72) | FAAHCNR1CNR2ALDH1A1MAPT | |
| SCHEMBL9986402 | 0.82 | FAAH (0.65) | FAAHCNR1CNR2ALDH1A1MAPT | |
| SCHEMBL8506453 | 0.82 | FAAH (0.75) | FAAHCNR1CNR2ALDH1A1MAPT | |
| SCHEMBL9958885 | 0.82 | LMNA (0.66) | FAAHCNR1CNR2ALDH1A1MAPT | |
| SCHEMBL6906595 | 0.82 | FAAH (0.65) | FAAHCNR1CNR2ALDH1A1MAPT | |
| SCHEMBL9447664 | 0.82 | FAAH (0.65) | FAAHCNR1CNR2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0191736-B1 | USE OF QUINOLINE DERIVATIVES FOR THE PROTECTION OF CROP PLANTS | CIBA-GEIGY AG (CH) | 1991-07-17 | — | — | EP | claimed |
| EP-0449989-A1 | 6,7 DIHYDROPYRROLO 3,4-c] PYRIDO 2,3-d] PYRIMIDINE DERIVATIVES | Sloan-Kettering Institute For Cancer Research (US) | 1991-10-09 | — | — | EP | disclosed |
| WO-1990007496-A1 | 6,7 DIHYDROPYRROLO[3,4-c] PYRIDO[2,3-d] PYRIMIDINE DERIVATIVES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-07-12 | — | — | WO | disclosed |