Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | MC4R | P32245 | 2/20 | 0.33 |
| ▸ | MC3R | P41968 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9827176 | 0.99 | GRIN2D (0.40) | HRH4HRH3GRIN2DGRIN3BGRIN1 | |
| SCHEMBL9828851 | 0.93 | GBA1 (0.38) | HRH4HRH3GRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL9827508 | 0.92 | GRIN2D (0.36) | HRH4HRH3GRIN2DGRIN3BGRIN1 | |
| SCHEMBL9828412 | 0.89 | CHRM2 (0.46) | HRH4HRH3GRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL9827919 | 0.88 | LMNA (0.47) | HRH4HRH3GRIN2DGRIN3BGRIN1 | |
| SCHEMBL7288371 | 0.86 | ADRA2A (0.35) | TSHRCYP2D6SMN1; SMN2TAAR1MC4R | |
| SCHEMBL9828326 | 0.85 | HRH4 (0.33) | HRH4HRH3GRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL9827568 | 0.84 | GRIN2D (0.33) | HRH4HRH3GRIN2DGRIN3BGRIN1 | |
| SCHEMBL7428749 | 0.82 | GBA1 (0.36) | HRH4HRH3GRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL9827936 | 0.82 | GBA1 (0.35) | HRH4HRH3GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302896-B1 | N-(W-SUBSTITUTED ALKYL)-N'-[(IMIDAZOLE-4-YL)ALKYL]GUANIDINE | CEDONA PHARMACEUTICALS B.V. (NL) | 1991-08-14 | — | — | EP | claimed |