Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.55 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.51 |
| ▸ | PYGL | P06737 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GGH | Q92820 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828789 | 1.00 | FOLH1 (0.55) | FOLH1NAALAD2PYGLMMP3HDAC8 | |
| SCHEMBL9829821 | 0.92 | PPARG (0.53) | FOLH1PYGLMMP3HDAC8PPARG | |
| SCHEMBL9829405 | 0.90 | FOLH1 (0.54) | FOLH1MMP3HDAC8PPARGPLK1 | |
| SCHEMBL8821265 | 0.88 | HDAC8 (0.47) | FOLH1MMP3HDAC8PPARGPLK1 | |
| SCHEMBL9830741 | 0.84 | MMP3 (0.54) | MMP3HDAC8PLK1NR1H4HPGD | |
| SCHEMBL9830733 | 0.84 | MMP3 (0.54) | MMP3HDAC8PLK1NR1H4HPGD | |
| SCHEMBL9716686 | 0.84 | FNTA (0.49) | FOLH1PYGLMMP3HDAC8PLK1 | |
| SCHEMBL9716690 | 0.84 | FNTA (0.49) | FOLH1PYGLMMP3HDAC8PLK1 | |
| SCHEMBL9828917 | 0.83 | MMP3 (0.53) | MMP3HDAC8PLK1NR1H4HPGD | |
| SCHEMBL18067781 | 0.83 | PLK1 (0.55) | MMP3HDAC8PLK1NR1H4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |