Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 4/20 | 0.49 |
| ▸ | FNTB | P49356 | 4/20 | 0.49 |
| ▸ | PYGL | P06737 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | CASR | P41180 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716686 | 1.00 | FNTA (0.49) | FNTAFNTBPYGLMMP3HDAC8 | |
| SCHEMBL8716172 | 0.96 | PYGL (0.52) | FNTAFNTBPYGLMMP3HDAC8 | |
| SCHEMBL8716175 | 0.96 | PYGL (0.52) | FNTAFNTBPYGLMMP3HDAC8 | |
| SCHEMBL9829821 | 0.87 | PPARG (0.53) | FNTAFNTBPYGLMMP3HDAC8 | |
| SCHEMBL27298381 | 0.86 | HPGDS (0.53) | PYGLMMP3HDAC8CASRMCHR1 | |
| SCHEMBL9829405 | 0.85 | FOLH1 (0.54) | FNTAFNTBMMP3HDAC8MCHR1 | |
| SCHEMBL10374890 | 0.84 | PYGL (0.52) | FNTAFNTBPYGLCASRCTSB | |
| SCHEMBL9828783 | 0.84 | FOLH1 (0.55) | PYGLMMP3HDAC8PLK1ALDH1A1 | |
| SCHEMBL9828789 | 0.84 | FOLH1 (0.55) | PYGLMMP3HDAC8PLK1ALDH1A1 | |
| SCHEMBL9828925 | 0.83 | MMP3 (0.53) | MMP3HDAC8PLK1CTSBCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178911-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1992-01-22 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0178911-A2 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1986-04-23 | — | — | EP | disclosed |