Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 13/20 | 0.64 |
| ▸ | CTSL | P07711 | 11/20 | 0.64 |
| ▸ | CTSK | P43235 | 8/20 | 0.64 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.53 |
| ▸ | ANPEP | P15144 | 2/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828850 | 1.00 | CTSS (0.64) | CTSSCTSLCTSKTAS1R3TAS1R1 | |
| SCHEMBL28022564 | 0.88 | CTSS (0.64) | CTSSCTSLCTSKTAS1R3TAS1R1 | |
| SCHEMBL9829685 | 0.85 | CTSL (0.67) | CTSSCTSLCTSKCTSB | |
| SCHEMBL9829689 | 0.85 | CTSL (0.67) | CTSSCTSLCTSKCTSB | |
| SCHEMBL24555259 | 0.84 | CA2 (0.52) | TAS1R3TAS1R1 | |
| SCHEMBL10953342 | 0.83 | CA2 (0.60) | CTSSCTSLCTSK | |
| SCHEMBL5637591 | 0.83 | CA2 (0.58) | TAS1R3TAS1R1 | |
| SCHEMBL9829827 | 0.83 | CA2 (0.58) | TAS1R3TAS1R1 | |
| SCHEMBL6183291 | 0.82 | CTSL (0.75) | CTSSCTSLCTSKCTSB | |
| SCHEMBL9830112 | 0.78 | CA2 (0.58) | CTSSCTSLCTSKTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |