Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 2/20 | 0.58 |
| ▸ | COPS5 | Q92905 | 2/20 | 0.58 |
| ▸ | CCR1 | P32246 | 3/20 | 0.55 |
| ▸ | CCR8 | P51685 | 3/20 | 0.55 |
| ▸ | CCR5 | P51681 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3272867 | 0.85 | PSMD14 (0.58) | PSMD14COPS5CCR1CCR8CCR5 | |
| SCHEMBL16938252 | 0.84 | PSMD14 (0.56) | PSMD14COPS5CCR1CCR8CCR5 | |
| SCHEMBL12564835 | 0.81 | CCR1 (0.67) | PSMD14COPS5CCR1CCR8CCR5 | |
| SCHEMBL28534276 | 0.80 | PSMD14 (0.51) | PSMD14COPS5CCR1CCR8CCR5 | |
| SCHEMBL2607397 | 0.78 | PSMD14 (0.68) | PSMD14COPS5CCR1CCR8CCR5 | |
| SCHEMBL28165068 | 0.78 | LMNA (0.66) | PSMD14COPS5CCR1CCR8CCR5 | |
| SCHEMBL16111888 | 0.78 | KDM4E (0.52) | CCR1CCR8KDM4ELMNATP53 | |
| SCHEMBL1187430 | 0.77 | HTT (0.72) | PSMD14COPS5CCR1CCR8CCR5 | |
| SCHEMBL29403673 | 0.77 | HTT (0.72) | PSMD14COPS5CCR1CCR8CCR5 | |
| SCHEMBL15863887 | 0.76 | HTT (0.70) | PSMD14COPS5CCR1CCR8CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239129-B1 | HYDROQUINOLINE COMPOUNDS, COMPOSITIONS CONTAINING SAME AND PROCESSES FOR PREPARING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-25 | — | — | EP | disclosed |
| US-4963566-A | ANTIULCER AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-16 | — | — | US | disclosed |
| EP-0239129-A2 | Hydroquinoline compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-09-30 | — | — | EP | disclosed |