Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 2/20 | 0.58 |
| ▸ | COPS5 | Q92905 | 2/20 | 0.58 |
| ▸ | CCR1 | P32246 | 3/20 | 0.55 |
| ▸ | CCR8 | P51685 | 3/20 | 0.55 |
| ▸ | CCR5 | P51681 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828866 | 0.85 | PSMD14 (0.58) | PSMD14COPS5CCR1CCR8CCR5 | |
| SCHEMBL10157939 | 0.85 | HTT (0.58) | PSMD14COPS5CCR1CCR8CCR5 | |
| SCHEMBL19725754 | 0.85 | KDM4E (0.50) | PSMD14COPS5L3MBTL1HTR1AADRA1D | |
| SCHEMBL16938252 | 0.84 | PSMD14 (0.56) | PSMD14COPS5CCR1CCR8CCR5 | |
| SCHEMBL474238 | 0.80 | KDM4E (0.50) | L3MBTL1HTTSLC6A2NPSR1KDM4E | |
| SCHEMBL22492368 | 0.80 | GABRA1 (0.45) | PSMD14COPS5L3MBTL1HTR1AADRA1D | |
| SCHEMBL28534276 | 0.80 | PSMD14 (0.51) | PSMD14COPS5CCR1CCR8CCR5 | |
| SCHEMBL2607397 | 0.78 | PSMD14 (0.68) | PSMD14COPS5CCR1CCR8CCR5 | |
| SCHEMBL12728621 | 0.78 | HTR1A (0.57) | PSMD14COPS5CCR1CCR8CCR5 | |
| SCHEMBL5542191 | 0.77 | PSMD14 (0.61) | PSMD14COPS5CCR1CCR8CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7692016-B2 | Process for the synthesis of quinoline derivatives | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2010-04-06 | — | — | US | claimed |
| US-20070123708-A1 | Process for the synthesis of quinoline derivatives | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-05-31 | — | — | US | claimed |
| WO-2007060685-A1 | AN IMPROVED PROCESS FOR THE SYNTHESIS OF QUINOLINE DERIVATIVES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2007-05-31 | — | — | WO | claimed |
| CN-1602194-A | Method for treating retroviral infections | UNIROYAL CHEM CO INC (US) | 2005-03-30 | — | — | CN | claimed |
| US-11773127-B2 | Compounds and methods for treating bacterial infections | WASHINGTON UNIVERSITY (US) | 2023-10-03 | — | — | US | disclosed |
| US-20210171563-A1 | COMPOUNDS AND METHODS FOR TREATING BACTERIAL INFECTIONS | WASHINGTON UNIVERSITY (US) | 2021-06-10 | — | — | US | disclosed |
| US-10113049-B2 | Thermoplastic resin composition | NIPPON NYUKAZAI CO., LTD. (JP) | 2018-10-30 | — | — | US | disclosed |
| US-20150329698-A1 | THERMOPLASTIC RESIN COMPOSITION | NIPPON NYUKAZAI CO., LTD. (JP) | 2015-11-19 | — | — | US | disclosed |
| CN-104159977-A | Thermoplastic resin composition | NIPPON NYUKAZAI CO LTD | 2014-11-19 | — | — | CN | disclosed |
| EP-2220076-B1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BOEHRINGER INGELHEIM INT (DE) | 2012-01-18 | — | — | EP | disclosed |
| US-20110118249-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BOEHRINGER INGLEHEIM INTERNATIONAL GMBH (DE) | 2011-05-19 | — | — | US | disclosed |
| US-7692016-B2 | Process for the synthesis of quinoline derivatives | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2010-04-06 | — | — | US | disclosed |
| WO-2009062285-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-22 | — | — | WO | disclosed |
| WO-2009062289-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-22 | — | — | WO | disclosed |
| WO-2009062308-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-22 | — | — | WO | disclosed |
| WO-2009062288-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-22 | — | — | WO | disclosed |
| US-20070123708-A1 | Process for the synthesis of quinoline derivatives | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-05-31 | — | — | US | disclosed |
| WO-2007060685-A1 | AN IMPROVED PROCESS FOR THE SYNTHESIS OF QUINOLINE DERIVATIVES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2007-05-31 | — | — | WO | disclosed |
| CN-1602194-A | Method for treating retroviral infections | UNIROYAL CHEM CO INC (US) | 2005-03-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123708-A1 | Process for the synthesis of quinoline derivatives | NDUFS4, NDUFS3, NDUFS5 | PSMD14 2299/4885COPS5 642/4885CCR1 4735/4885 |
| US-20210171563-A1 | COMPOUNDS AND METHODS FOR TREATING BACTERIAL INFECTIONS | MMP8, ELANE, MPO | PSMD14 2801/4885COPS5 2026/4885CCR1 602/4885 |
| US-20110118249-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | RTF2, CCNY, RTF1 | PSMD14 1970/4885COPS5 1221/4885CCR1 181/4885 |
| US-11773127-B2 | Compounds and methods for treating bacterial infections | MMP8, ELANE, MPO | PSMD14 2801/4885COPS5 2026/4885CCR1 602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.