Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 4/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1862935 | 0.80 | AVPR1A (0.46) | AVPR1AMMP2GPBAR1PIM1HSD17B3 | |
| SCHEMBL28650278 | 0.74 | MAPT (0.53) | KDM4EALDH1A1GAAMAPK1KMT2A | |
| SCHEMBL28092685 | 0.74 | KMT2A (0.46) | AVPR1AMMP2HSD17B3KDM4EALDH1A1 | |
| SCHEMBL28297314 | 0.72 | AVPR1A (0.38) | AVPR1AMMP2GPBAR1PIM1HSD17B3 | |
| SCHEMBL29941296 | 0.71 | AVPR1A (0.56) | AVPR1AGPBAR1HSD17B3ALDH1A1HSD11B1 | |
| SCHEMBL3663893 | 0.71 | AVPR1A (0.56) | AVPR1AGPBAR1HSD17B3ALDH1A1HSD11B1 | |
| SCHEMBL3661398 | 0.70 | MAPK1 (0.50) | AVPR1APIM1MAPK1KMT2AMEN1 | |
| SCHEMBL25937281 | 0.68 | AVPR1A (0.52) | AVPR1AMMP2GPBAR1HSD17B3ALDH1A1 | |
| SCHEMBL30379071 | 0.68 | HTT (0.57) | AVPR1AGPBAR1HSD17B3ALDH1A1HSD11B1 | |
| SCHEMBL26088243 | 0.68 | HTT (0.57) | AVPR1AGPBAR1HSD17B3ALDH1A1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0197294-B1 | BETA-LACTAM ANTIBIOTICS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | BAYER AG (DE) | 1991-04-03 | — | — | EP | disclosed |
| US-4734407-A | ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1988-03-29 | — | — | US | disclosed |