Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 3/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5458675 | 0.84 | BRPF1 (0.40) | BRPF1BRD4MEN1GAAKMT2A | |
| SCHEMBL1862935 | 0.75 | AVPR1A (0.46) | AVPR1ABRPF1PIM1BRD4GAA | |
| SCHEMBL94614 | 0.74 | SMN1; SMN2 (0.41) | AVPR1ABRPF1PIM1BRD4MEN1 | |
| SCHEMBL9828967 | 0.72 | AVPR1A (0.40) | AVPR1ABRPF1PIM1MEN1GAA | |
| SCHEMBL1383225 | 0.70 | ALDH1A1 (0.44) | MEN1GAAKMT2AHPGD | |
| SCHEMBL11070863 | 0.70 | — | — | |
| SCHEMBL7757772 | 0.69 | ADRA2A (0.46) | — | |
| SCHEMBL28833094 | 0.69 | BRD4 (0.41) | AVPR1ABRPF1PIM1BRD4MEN1 | |
| SCHEMBL3661398 | 0.68 | MAPK1 (0.50) | AVPR1APIM1MEN1KMT2AMAPK1 | |
| SCHEMBL31512482 | 0.68 | AVPR1A (0.39) | AVPR1ABRPF1PIM1BRD4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106029076-B | Benzo piperazine composition as BET bromine domain inhibitor | 福马疗法公司 | 2019-06-07 | — | — | CN | disclosed |