Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.64 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.64 |
| ▸ | CA2 | P00918 | 4/20 | 0.59 |
| ▸ | CA1 | P00915 | 3/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | GRN | P28799 | 3/20 | 0.56 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.56 |
| ▸ | PLK1 | P53350 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829334 | 1.00 | MAPT (0.69) | MAPTTAS1R3TAS1R1CA2CA1 | |
| SCHEMBL4173638 | 0.92 | TAS1R3 (0.76) | MAPTTAS1R3TAS1R1CA2CA1 | |
| SCHEMBL28965835 | 0.83 | PTPN1 (0.66) | CA2CA1CA12CA9PLK1 | |
| SCHEMBL28965836 | 0.83 | PTPN1 (0.66) | CA2CA1CA12CA9PLK1 | |
| SCHEMBL18068386 | 0.82 | CA2 (0.64) | CA2CA1CA12CA9PLK1 | |
| SCHEMBL15200061 | 0.81 | MAPT (0.48) | MAPTTAS1R3TAS1R1CA2CA1 | |
| SCHEMBL16124678 | 0.81 | MAPT (0.65) | MAPTTAS1R3TAS1R1GAA | |
| SCHEMBL19135349 | 0.81 | LNPEP (0.48) | MAPTTAS1R3TAS1R1CA2CA1 | |
| SCHEMBL31611853 | 0.80 | CA2 (0.68) | TAS1R3TAS1R1CA2CA1CA12 | |
| SCHEMBL4160513 | 0.80 | CA2 (0.68) | TAS1R3TAS1R1CA2CA1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |