Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 16/20 | 0.39 |
| ▸ | SLC16A1 | P53985 | 13/20 | 0.39 |
| ▸ | MCTS1 | Q9ULC4 | 7/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833063 | 0.88 | TYR (0.40) | TYRF10NPSR1 | |
| SCHEMBL9831414 | 0.81 | SMN1; SMN2 (0.56) | SLC16A3SLC16A1MCTS1 | |
| SCHEMBL9829861 | 0.79 | L3MBTL1 (0.49) | SLC16A3SLC16A1MCTS1 | |
| SCHEMBL17232511 | 0.73 | NOTUM (0.38) | TYRF10NPSR1 | |
| SCHEMBL4068333 | 0.73 | NOTUM (0.57) | F10NPSR1 | |
| SCHEMBL8310144 | 0.72 | CA1 (0.38) | — | |
| SCHEMBL3369897 | 0.70 | NOTUM (0.38) | TYRF10NPSR1 | |
| SCHEMBL9830636 | 0.70 | POLB (0.54) | SLC16A3SLC16A1MCTS1 | |
| SCHEMBL17229342 | 0.70 | SMN1; SMN2 (0.40) | F10 | |
| SCHEMBL9832101 | 0.69 | POLB (0.53) | SLC16A3SLC16A1MCTS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220573-B1 | HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 1991-12-11 | — | — | EP | claimed |
| US-4774253-A | ETHER,-ACIDS, ESTERS OR AMIDES | HOFFMANN-LA ROCHE INC. (US) | 1988-09-27 | — | — | US | claimed |
| EP-0220573-A1 | Heterocyclic compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1987-05-06 | — | — | EP | claimed |
| EP-0220573-B1 | HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 1991-12-11 | — | — | EP | disclosed |
| US-4774253-A | ETHER,-ACIDS, ESTERS OR AMIDES | HOFFMANN-LA ROCHE INC. (US) | 1988-09-27 | — | — | US | disclosed |
| EP-0220573-A1 | Heterocyclic compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1987-05-06 | — | — | EP | disclosed |