Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 3/20 | 0.58 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.58 |
| ▸ | ITGAL | P20701 | 3/20 | 0.58 |
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.47 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.45 |
| ▸ | GGT1 | P19440 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208664 | 0.88 | ITGB2 (0.58) | ITGB2ICAM1ITGALCA1CA2 | |
| SCHEMBL10658536 | 0.82 | CA1 (0.71) | ITGB2ICAM1ITGALCA1CA2 | |
| SCHEMBL163397 | 0.79 | ITGB2 (0.60) | ITGB2ICAM1ITGALCA1CA2 | |
| SCHEMBL27413426 | 0.79 | ITGB2 (0.67) | ITGB2ICAM1ITGALCA1CA2 | |
| SCHEMBL151336 | 0.79 | ITGB2 (0.60) | ITGB2ICAM1ITGALCA1CA2 | |
| SCHEMBL27043238 | 0.79 | ITGB2 (0.60) | ITGB2ICAM1ITGALCA1CA2 | |
| Hydrochloric Acid SCHEMBL11744091 | 0.77 | ITGB2 (0.59) | ITGB2ICAM1ITGALCA1CA2 | |
| SCHEMBL3378643 | 0.77 | CYP3A4 (0.61) | ITGB2ICAM1ITGALCA1CA2 | |
| SCHEMBL6026427 | 0.76 | ITGB2 (0.64) | ITGB2ICAM1ITGALCA1CA2 | |
| SCHEMBL1666697 | 0.76 | ALDH1A1 (0.58) | ITGB2ICAM1ITGALCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | claimed |