Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828732 | 0.83 | ALOX12 (0.40) | ALOX12HTR2CCES1MEN1ALDH1A1 | |
| SCHEMBL9827964 | 0.83 | ALOX12 (0.40) | ALOX12HTR2CCES1MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9827615 | 0.82 | MEN1 (0.40) | ALOX12HTR2CCES1MEN1ALDH1A1 | |
| SCHEMBL3312853 | 0.77 | CES1 (0.44) | ALOX12HTR2CCES1MEN1ALDH1A1 | |
| SCHEMBL2625788 | 0.75 | ALOX12 (0.60) | ALOX12HTR2CCES1MEN1ALDH1A1 | |
| SCHEMBL9828856 | 0.75 | PTGER4 (0.39) | ALOX12CES1MEN1KMT2AHTR1A | |
| Hydrochloric Acid SCHEMBL10412817 | 0.74 | PTGER4 (0.38) | ALOX12CES1MEN1ALDH1A1KMT2A | |
| SCHEMBL24358931 | 0.74 | ALOX12 (0.42) | ALOX12HTR2CCES1MEN1ALDH1A1 | |
| SCHEMBL20348492 | 0.74 | ALOX12 (0.42) | ALOX12HTR2CCES1MEN1ALDH1A1 | |
| SCHEMBL10264825 | 0.74 | DRD2 (0.44) | HTR2CHTR1APTGER4PTGER2HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239129-B1 | HYDROQUINOLINE COMPOUNDS, COMPOSITIONS CONTAINING SAME AND PROCESSES FOR PREPARING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-25 | — | — | EP | disclosed |
| US-4963566-A | ANTIULCER AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-16 | — | — | US | disclosed |
| EP-0239129-A2 | Hydroquinoline compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-09-30 | — | — | EP | disclosed |