Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10412817 | 0.99 | PTGER4 (0.38) | PTGER4PTGER2ALOX12MCL1HTR1A | |
| SCHEMBL9827964 | 0.78 | ALOX12 (0.40) | PTGER4PTGER2ALOX12MCL1HTR1A | |
| SCHEMBL9829802 | 0.75 | ALOX12 (0.40) | PTGER4PTGER2ALOX12MCL1HTR1A | |
| SCHEMBL9828732 | 0.75 | ALOX12 (0.40) | PTGER4PTGER2ALOX12HTR1ANOTUM | |
| Hydrochloric Acid SCHEMBL9827615 | 0.74 | MEN1 (0.40) | PTGER4PTGER2ALOX12HTR1AMEN1 | |
| SCHEMBL6643060 | 0.74 | NOTUM (0.44) | ALOX12MCL1NOTUMMEN1KMT2A | |
| SCHEMBL10264825 | 0.73 | DRD2 (0.44) | PTGER4PTGER2HTR1ANOTUM | |
| SCHEMBL29800852 | 0.71 | NOTUM (0.40) | PTGER4PTGER2HTR1ANOTUM | |
| SCHEMBL11837962 | 0.70 | RAB9A (0.47) | ALOX12MEN1KMT2ACES1 | |
| SCHEMBL13449499 | 0.69 | NOTUM (0.43) | PTGER4PTGER2NOTUMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239129-B1 | HYDROQUINOLINE COMPOUNDS, COMPOSITIONS CONTAINING SAME AND PROCESSES FOR PREPARING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-25 | — | — | EP | disclosed |