Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | S100B | P04271 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826402 | 0.79 | HPGD (0.50) | TERTALDH1A1MAPTL3MBTL1ALOX15 | |
| SCHEMBL16056664 | 0.79 | MAPT (0.46) | TERTALDH1A1MAPTL3MBTL1ALOX15 | |
| SCHEMBL17893582 | 0.79 | ALDH1A1 (0.46) | TERTALDH1A1MAPTL3MBTL1ALOX15 | |
| SCHEMBL28867024 | 0.79 | ALDH1A1 (0.46) | TERTALDH1A1MAPTL3MBTL1ALOX15 | |
| SCHEMBL29937495 | 0.79 | ALDH1A1 (0.46) | TERTALDH1A1MAPTL3MBTL1ALOX15 | |
| SCHEMBL10277024 | 0.79 | MEN1 (0.46) | TERTALDH1A1MAPTL3MBTL1ALOX15 | |
| SCHEMBL798142 | 0.79 | HPGD (0.54) | TERTALDH1A1MAPTL3MBTL1ALOX15 | |
| SCHEMBL16056360 | 0.78 | ALDH1A1 (0.49) | TERTALDH1A1MAPTL3MBTL1ALOX15 | |
| SCHEMBL23457073 | 0.77 | TERT (0.44) | TERTALDH1A1MAPTL3MBTL1ALOX15 | |
| SCHEMBL21736791 | 0.77 | MAPT (0.41) | TERTALDH1A1MAPTL3MBTL1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449989-A1 | 6,7 DIHYDROPYRROLO 3,4-c] PYRIDO 2,3-d] PYRIMIDINE DERIVATIVES | Sloan-Kettering Institute For Cancer Research (US) | 1991-10-09 | — | — | EP | claimed |
| WO-1990007496-A1 | 6,7 DIHYDROPYRROLO[3,4-c] PYRIDO[2,3-d] PYRIMIDINE DERIVATIVES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-07-12 | — | — | WO | claimed |