Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.46 |
| ▸ | GRN | P28799 | 3/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830000 | 1.00 | CA2 (0.47) | CA2CA1FOLH1GRNSORT1 | |
| SCHEMBL10660226 | 0.92 | CA2 (0.47) | CA2CA1GRNSORT1CA12 | |
| SCHEMBL10660207 | 0.92 | CA2 (0.47) | CA2CA1GRNSORT1CA12 | |
| SCHEMBL9830052 | 0.92 | PSMB5 (0.49) | CA2CA1GRNSORT1DGAT1 | |
| SCHEMBL9830035 | 0.92 | PSMB5 (0.49) | CA2CA1GRNSORT1DGAT1 | |
| SCHEMBL316943 | 0.91 | OPRD1 (0.42) | FOLH1GRNSORT1 | |
| SCHEMBL9409319 | 0.89 | FOLH1 (0.46) | FOLH1MMEPSMB5CTSL | |
| SCHEMBL5524927 | 0.89 | FOLH1 (0.41) | CA2CA1FOLH1GRNSORT1 | |
| SCHEMBL30400489 | 0.84 | NPY4R (0.52) | FOLH1 | |
| SCHEMBL4671172 | 0.83 | OPRD1 (0.42) | CA2CA1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |