Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 6/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | GRPR | P30550 | 1/20 | 0.39 |
| ▸ | GRN | P28799 | 1/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17925467 | 0.93 | OPRM1 (0.46) | OPRD1OPRM1OPRK1GRPR | |
| SCHEMBL1275443 | 0.93 | OPRM1 (0.46) | OPRD1OPRM1OPRK1GRPR | |
| SCHEMBL1674833 | 0.93 | OPRM1 (0.46) | OPRD1OPRM1OPRK1GRPR | |
| SCHEMBL11330795 | 0.92 | OPRM1 (0.42) | OPRD1OPRM1OPRK1GRPRGRN | |
| Water SCHEMBL28629638 | 0.92 | OPRM1 (0.46) | OPRD1OPRM1OPRK1GRPR | |
| Hydrochloric Acid SCHEMBL30196080 | 0.92 | OPRM1 (0.46) | OPRD1OPRM1OPRK1GRPR | |
| Water SCHEMBL1433018 | 0.92 | OPRM1 (0.46) | OPRD1OPRM1OPRK1GRPR | |
| Water SCHEMBL1433025 | 0.92 | OPRM1 (0.46) | OPRD1OPRM1OPRK1GRPR | |
| SCHEMBL9830023 | 0.91 | CA2 (0.47) | FOLH1GRNSORT1 | |
| SCHEMBL9830000 | 0.91 | CA2 (0.47) | FOLH1GRNSORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4292404-A | Method for determining the activity of the angiotensin-converting enzyme | FUJIZOKI PHARMACEUTICAL CO., LTD. (JP) | 1981-09-29 | — | — | US | claimed |
| JP-57036997-A | — | — | None | — | — | JP | disclosed |
| EP-4630574-A1 | TEST SYSTEM FOR MEASURING THE ENZYME ACTIVITY OF ANGIOTENSIN-CONVERTING ENZYME (ACE) | DiaSys Diagnostic Systems GmbH (DE) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024121040-A1 | TEST SYSTEM FOR MEASURING THE ENZYME ACTIVITY OF ANGIOTENSIN-CONVERTING ENZYME (ACE) | DIASYS DIAGNOSTIC SYSTEMS GMBH (DE) | 2024-06-13 | — | — | WO | disclosed |
| US-8092795-B2 | Liquid seasoning | KAO CORPORATION (JP) | 2012-01-10 | — | — | US | disclosed |
| US-8053014-B2 | Liquid seasoning | KAO CORPORATION (JP) | 2011-11-08 | — | — | US | disclosed |
| US-20110183366-A1 | Methods for achieving a protective ACE2 expression level to treat kidney disease and hypertension | BATLLE DANIEL | 2011-07-28 | — | — | US | disclosed |
| US-7887868-B2 | low-salt soy sauce having an antihypertensive effect; contains 3.55% or less by weight of sodium, 0.5% to 3.6% by weight of potassium, 0.05 to 20% by weight of at least one polyphenol | KAO CORPORATION (JP) | 2011-02-15 | — | — | US | disclosed |
| US-7727524-B2 | Low sodium liquid seasoning with anti-hypertensive activity | KAO CORPORATION (JP) | 2010-06-01 | — | — | US | disclosed |
| US-20100092649-A1 | LIQUID SEASONING | KAO CORPORATION (JP) | 2010-04-15 | — | — | US | disclosed |
| US-20060275346-A1 | Liquid seasoning | KAO CORPORATION (JP) | 2006-12-07 | — | — | US | disclosed |
| US-20060115518-A1 | Liquid seasoning | KAO CORPORATION (JP) | 2006-06-01 | — | — | US | disclosed |
| US-20060115517-A1 | Liquid seasoning | KAO CORPORATION (JP) | 2006-06-01 | — | — | US | disclosed |
| US-20060105065-A1 | Liquid seasoning | KAO CORPORATION (JP) | 2006-05-18 | — | — | US | disclosed |
| WO-2005097109-A1 | METHODS FOR ACHIEVING A PROTECTIVE ACE2 EXPRESSION LEVEL | BATLLE DANIEL (US) | 2005-10-20 | — | — | WO | disclosed |
| US-20040014670-A1 | Inhibitors of angiotensin converting enzyme | AJINOMOTO CO. INC (JP) | 2004-01-22 | — | — | US | disclosed |
| EP-1352911-A1 | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | Ajinomoto Co., Inc. (JP) | 2003-10-15 | — | — | EP | disclosed |
| US-4407944-A | Method for determining the activity of the angiotensin-converting enzyme | FUJIZOKI PHARMACEUTICAL CO., LTD. (JP) | 1983-10-04 | — | — | US | disclosed |
| JP-S5736997-A | DETERMINATION OF ACTIVITY OF ANGIOTENSINASE | FUJIREBIO INC | 1982-02-27 | — | — | JP | disclosed |
| US-4292404-A | Method for determining the activity of the angiotensin-converting enzyme | FUJIZOKI PHARMACEUTICAL CO., LTD. (JP) | 1981-09-29 | — | — | US | disclosed |