Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.45 |
| ▸ | RAB9A | P51151 | 10/20 | 0.43 |
| ▸ | NPC1 | O15118 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830797 | 0.80 | RAB9A (0.39) | KDM4ERAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL9829473 | 0.79 | KDM4E (0.42) | KDM4ERAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9823518 | 0.78 | KDM4E (0.45) | KDM4ERAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9830211 | 0.76 | KDM4E (0.46) | KDM4ERAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9832616 | 0.74 | MEN1 (0.63) | KDM4ERAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9629549 | 0.68 | KDM4E (0.46) | KDM4EALDH1A1 | |
| SCHEMBL9831169 | 0.67 | RAB9A (0.36) | KDM4ERAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9830723 | 0.67 | MAPT (0.41) | KDM4ERAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9823766 | 0.67 | TDP1 (0.46) | KDM4ERAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9823494 | 0.67 | KDM4E (0.41) | KDM4ERAB9ANPC1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321115-B1 | CARBOXAMIDE DERIVATIVES HAVING TETRAZOLE AND THIAZOLE RINGS AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4946855-A | ANTIALLERGIC | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0321115-A1 | Carboxamide derivatives having tetrazole and thiazole rings and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-21 | — | — | EP | disclosed |