Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.63 |
| ▸ | RAB9A | P51151 | 9/20 | 0.63 |
| ▸ | NPC1 | O15118 | 8/20 | 0.63 |
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 6/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.49 |
| ▸ | CLK1 | P49759 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829808 | 0.82 | RAB9A (0.58) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL9829473 | 0.81 | KDM4E (0.42) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL9831525 | 0.80 | NPC1 (0.60) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL9832583 | 0.80 | LMNA (0.57) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL9831311 | 0.78 | LMNA (0.60) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL9829907 | 0.78 | LMNA (0.59) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL9831892 | 0.78 | ABL1 (0.60) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL9829872 | 0.77 | RAB9A (0.62) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL9832536 | 0.77 | LMNA (0.62) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL9830542 | 0.76 | ALDH1A1 (0.66) | MEN1KMT2AALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321115-B1 | CARBOXAMIDE DERIVATIVES HAVING TETRAZOLE AND THIAZOLE RINGS AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4946855-A | ANTIALLERGIC | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0321115-A1 | Carboxamide derivatives having tetrazole and thiazole rings and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-21 | — | — | EP | disclosed |