Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | DDX3X | O00571 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830797 | 0.89 | RAB9A (0.39) | KDM4EMAPTRAB9AKMT2ANPC1 | |
| SCHEMBL9830151 | 0.85 | MAPT (0.46) | KDM4EMAPTRAB9AKMT2ANPC1 | |
| SCHEMBL9831158 | 0.80 | CDC25A (0.49) | KDM4EMAPTRAB9AKMT2ANPC1 | |
| SCHEMBL9823493 | 0.78 | KDM4E (0.46) | KDM4EMAPTRAB9AKMT2ANPC1 | |
| SCHEMBL9830723 | 0.76 | MAPT (0.41) | KDM4EMAPTRAB9AKMT2ANPC1 | |
| SCHEMBL9831169 | 0.76 | RAB9A (0.36) | KDM4EMAPTRAB9AKMT2ANPC1 | |
| SCHEMBL9830065 | 0.76 | KDM4E (0.45) | KDM4ERAB9AKMT2ANPC1ADORA3 | |
| SCHEMBL9831938 | 0.75 | PPARA (0.49) | KDM4EMAPTRAB9AKMT2ANPC1 | |
| SCHEMBL9829242 | 0.75 | ADORA3 (0.60) | KDM4EMAPTRAB9AKMT2ANPC1 | |
| Monoethanolamine SCHEMBL9830948 | 0.74 | CDC25A (0.44) | KDM4EMAPTRAB9AKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321115-B1 | CARBOXAMIDE DERIVATIVES HAVING TETRAZOLE AND THIAZOLE RINGS AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4946855-A | ANTIALLERGIC | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0321115-A1 | Carboxamide derivatives having tetrazole and thiazole rings and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-21 | — | — | EP | disclosed |