Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1390870 | 0.85 | NQO1 (0.67) | NQO1SMN1; SMN2KDM4EALDH1A1TSHR | |
| SCHEMBL8751807 | 0.84 | NQO1 (0.63) | NQO1SMN1; SMN2KDM4EALDH1A1TSHR | |
| SCHEMBL26627775 | 0.84 | L3MBTL1 (0.46) | NQO1SMN1; SMN2KDM4EALDH1A1TSHR | |
| SCHEMBL23906791 | 0.83 | NQO1 (0.50) | NQO1SMN1; SMN2KDM4EALDH1A1TSHR | |
| SCHEMBL27504104 | 0.83 | NQO1 (0.50) | NQO1SMN1; SMN2ALDH1A1TSHRTDP1 | |
| SCHEMBL16033984 | 0.82 | NQO1 (0.34) | NQO1SMN1; SMN2KDM4EALDH1A1NPC1 | |
| SCHEMBL3473670 | 0.81 | APP (0.37) | NQO1SMN1; SMN2KDM4EALDH1A1MAPT | |
| SCHEMBL14175640 | 0.79 | NQO1 (0.58) | NQO1SMN1; SMN2KDM4EALDH1A1TSHR | |
| SCHEMBL6158908 | 0.79 | LTA4H (0.61) | NQO1SMN1; SMN2KDM4EALDH1A1TSHR | |
| SCHEMBL27730066 | 0.78 | NQO1 (0.50) | NQO1KDM4EALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199281-B1 | PYRIDAZINONE DERIVATIVES, PREPARATION THEREOF, AND INSECTICIDAL, ACARICIDAL, NEMATICIDAL, FUNGICIDAL COMPOSITIONS | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1991-07-10 | — | — | EP | disclosed |
| US-4837217-A | Pyridazinone derivatives, preparation thereof, and insecticidal, acaricidal, nematicidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1989-06-06 | — | — | US | disclosed |