Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.37 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11474319 | 0.83 | TAAR1 (0.39) | APPMAOB | |
| SCHEMBL3589633 | 0.83 | NQO1 (0.50) | APPNQO1MMP2MMP3MMP9 | |
| SCHEMBL25986811 | 0.82 | LTA4H (0.50) | APPNQO1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2982877 | 0.81 | ACACB (0.42) | APPKDM4EMAPT | |
| SCHEMBL9830128 | 0.81 | NQO1 (0.46) | NQO1HPGDALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL14341660 | 0.80 | APP (0.47) | APPMAOBIDO1SMN1; SMN2 | |
| SCHEMBL2127451 | 0.80 | SMN1; SMN2 (0.47) | NQO1MAOBHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL11357207 | 0.78 | MMP2 (0.40) | APPNQO1MMP2MMP3MMP9 | |
| SCHEMBL7855924 | 0.78 | APP (0.37) | APPNQO1MMP2MMP3MMP9 | |
| SCHEMBL6160052 | 0.78 | FYN (0.47) | APPNQO1MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101506267-B | Weather-resistant and heat-stable polymers with improved flow components | SABIC INNOVATIVE PLASTICS IP | 2014-08-27 | — | — | CN | disclosed |
| CN-101160340-B | Transparent compositions, methods for the preparation thereof, and articles derived therefrom | GEN ELECTRIC | 2012-06-27 | — | — | CN | disclosed |
| US-7838602-B2 | Weatherable, thermostable polymers having improved flow composition | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-11-23 | — | — | US | disclosed |
| US-7605221-B2 | Aromatic polycarbonateester block or random copolymer and polysiloxane blend primarily containing isophthalic and terephthalic acids, resorcinol and dimethylsilanediol monomers; films are radiation transparent; improved ductility at lower temperatures; aircraft components | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2009-10-20 | — | — | US | disclosed |
| CN-101506267-A | Weather-and heat-stable polymers with improved flow components | SABIC INNOVATIVE PLASTICS IP (NL) | 2009-08-12 | — | — | CN | disclosed |
| EP-2032624-A1 | WEATHERABLE, THERMOSTABLE POLYMERS HAVING IMPROVED FLOW COMPOSITION | Sabic Innovative Plastics IP B.V. (NL) | 2009-03-11 | — | — | EP | disclosed |
| US-7432327-B2 | Transparent polymeric compositions comprising polysiloxane-polycarbonate copolymer, articles made therefrom and methods of making same | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-10-07 | — | — | US | disclosed |
| CN-101160340-A | Transparent compositions, methods for the preparation thereof, and articles derived therefrom | GEN ELECTRIC (US) | 2008-04-09 | — | — | CN | disclosed |
| US-7321014-B2 | Transparent compositions, methods for the preparation thereof, and articles derived therefrom | GENERAL ELECTRIC COMPANY (US) | 2008-01-22 | — | — | US | disclosed |
| WO-2008002757-A1 | WEATHERABLE, THERMOSTABLE POLYMERS HAVING IMPROVED FLOW COMPOSITION | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-01-03 | — | — | WO | disclosed |
| US-20060142527-A1 | Transparent compositions, methods for the preparation thereof, and articles derived therefrom | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2006-06-29 | — | — | US | disclosed |
| US-6924388-B2 | Bicyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-08-02 | — | — | US | disclosed |
| US-20050159577-A1 | Weatherable, thermostable polymers having improved flow composition | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2005-07-21 | — | — | US | disclosed |
| US-20040092594-A1 | Bicyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-05-13 | — | — | US | disclosed |
| US-6632963-B1 | Are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular and ophthalmological disorders, as well as for the treatment of | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2003-10-14 | — | — | US | disclosed |
| CN-1346828-A | Dicyclic aromatic compound and use thereof in human or animal medicine and cosmetic process | CT INTERNAT DE RES ES DERMATOL (FR) | 2002-05-01 | — | — | CN | disclosed |
| CN-1241558-A | Bicyclic aromatic compounds and their use in human or veterinary medicine and in cosmetic processes | GALDERMA RESEARCH DEV S N C (FR) | 2000-01-19 | — | — | CN | disclosed |
| EP-0199281-B1 | PYRIDAZINONE DERIVATIVES, PREPARATION THEREOF, AND INSECTICIDAL, ACARICIDAL, NEMATICIDAL, FUNGICIDAL COMPOSITIONS | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1991-07-10 | — | — | EP | disclosed |
| US-4837217-A | Pyridazinone derivatives, preparation thereof, and insecticidal, acaricidal, nematicidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1989-06-06 | — | — | US | disclosed |
| EP-0199281-A2 | Pyridazinone derivatives, preparation thereof, and insecticidal, acaricidal, nematicidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-10-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092594-A1 | Bicyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof | AHR, TYR, MC1R | APP 2281/4885NQO1 624/4885MMP2 1612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.