Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 9/20 | 0.64 |
| ▸ | CTSK | P43235 | 5/20 | 0.64 |
| ▸ | CTSB | P07858 | 4/20 | 0.64 |
| ▸ | CTSS | P25774 | 3/20 | 0.64 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830319 | 1.00 | CTSL (0.64) | CTSLCTSKCTSBCTSSPSMB5 | |
| SCHEMBL9829689 | 0.86 | CTSL (0.67) | CTSLCTSKCTSBCTSSPSMB5 | |
| SCHEMBL9829685 | 0.86 | CTSL (0.67) | CTSLCTSKCTSBCTSSPSMB5 | |
| SCHEMBL2934284 | 0.85 | PSMB5 (0.62) | CTSLCTSKCTSBCTSSPSMB5 | |
| SCHEMBL2158906 | 0.84 | CTSL (0.67) | CTSLCTSKCTSBCTSSPSMB5 | |
| SCHEMBL2158900 | 0.84 | CTSL (0.67) | CTSLCTSKCTSBCTSSPSMB5 | |
| SCHEMBL4465251 | 0.84 | CTSL (0.67) | CTSLCTSKCTSBCTSSPSMB5 | |
| SCHEMBL9830704 | 0.83 | CTSL (0.56) | CTSLCTSKCTSBCTSSCA2 | |
| SCHEMBL9830711 | 0.83 | CTSL (0.56) | CTSLCTSKCTSBCTSSCA2 | |
| SCHEMBL23470237 | 0.82 | CTSL (0.70) | CTSLCTSKCTSBCTSSPSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |