Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.56 |
| ▸ | CTSB | P07858 | 2/20 | 0.56 |
| ▸ | CTSS | P25774 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 1/20 | 0.56 |
| ▸ | MME | P08473 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | GRN | P28799 | 2/20 | 0.51 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830704 | 1.00 | CTSL (0.56) | CTSLCTSBCTSSCTSKMME | |
| SCHEMBL4465251 | 0.87 | CTSL (0.67) | CTSLCTSBCTSSCTSKMME | |
| SCHEMBL2158906 | 0.87 | CTSL (0.67) | CTSLCTSBCTSSCTSKMME | |
| SCHEMBL2158900 | 0.87 | CTSL (0.67) | CTSLCTSBCTSSCTSKMME | |
| SCHEMBL27989559 | 0.86 | CASP3 (0.54) | MMEKMT2AALDH1A1CA2CA1 | |
| SCHEMBL11318126 | 0.86 | CTSL (0.51) | CTSLCTSBCTSSCTSKKMT2A | |
| SCHEMBL9002994 | 0.85 | ERAP2 (0.51) | CTSLCTSBCTSSCTSKKMT2A | |
| SCHEMBL31294431 | 0.84 | KMT2A (0.52) | KMT2AALDH1A1CA2CA1MEN1 | |
| SCHEMBL9830319 | 0.83 | CTSL (0.64) | CTSLCTSBCTSSCTSKMME | |
| SCHEMBL9830316 | 0.83 | CTSL (0.64) | CTSLCTSBCTSSCTSKMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |
| US-4257940-A | Valylleucyllysine derivatives, process for producing same and method for measuring activity of enzymes using same | TORII & CO., LTD. (JP) | 1981-03-24 | — | — | US | disclosed |