Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 2/20 | 0.62 |
| ▸ | CTSL | P07711 | 5/20 | 0.62 |
| ▸ | CTSS | P25774 | 2/20 | 0.62 |
| ▸ | CTSK | P43235 | 2/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | CTSB | P07858 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ACE | P12821 | 2/20 | 0.54 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12516923 | 0.95 | CTSB (0.62) | PSMB5CTSLCTSSCTSKPTPN1 | |
| SCHEMBL11319330 | 0.88 | PSMB5 (0.59) | PSMB5CTSLCTSSCTSKCTSB | |
| SCHEMBL10119250 | 0.86 | PSMB5 (0.65) | PSMB5CTSLCTSSCTSKPTPN1 | |
| SCHEMBL7318555 | 0.86 | PSMB5 (0.65) | PSMB5CTSLCTSSCTSKPTPN1 | |
| SCHEMBL11116006 | 0.86 | CTSS (0.60) | CTSSCTSK | |
| SCHEMBL11116015 | 0.86 | CTSS (0.60) | CTSSCTSK | |
| SCHEMBL9830316 | 0.85 | CTSL (0.64) | PSMB5CTSLCTSSCTSKCTSB | |
| SCHEMBL9830319 | 0.85 | CTSL (0.64) | PSMB5CTSLCTSSCTSKCTSB | |
| SCHEMBL4357736 | 0.84 | ACE (0.68) | PSMB5CTSLCTSSCTSKPTPN1 | |
| SCHEMBL4356229 | 0.84 | ACE (0.68) | PSMB5CTSLCTSSCTSKPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2229440-A2 | RECOMBINANT ELASTASE PROTEINS AND METHODS OF MANUFACTURING AND USE THEREOF | Proteon Therapeutics, Inc. (US) | 2010-09-22 | — | — | EP | disclosed |
| WO-2009079220-A2 | RECOMBINANT ELASTASE PROTEINS AND METHODS OF MANUFACTURING AND USE THEREOF | PROTEON THERAPEUTICS, INC. (US) | 2009-06-25 | — | — | WO | disclosed |
| US-5220029-A | N-acyl derivatives of thiazolinone hydazones | VITEK SYSTEMS, INC. (US) | 1993-06-15 | — | — | US | disclosed |
| US-RE34284-E | Contacting sample with enzyme reactive acyl thiazolinone hydrazone compound, adding oxidative coupling agents and oxidizing agents, monitoring increase in absorbance | BIOMERIEUX VITEK, INC. (US) | 1993-06-15 | — | — | US | disclosed |
| US-4950593-A | USING THIAZOLINONE HYDRAZONE | VITEK SYSTEMS, INC. (US) | 1990-08-21 | — | — | US | disclosed |
| US-4308201-A | SUBSTRATES; MEDICAL DIAGNOSIS | TORII & CO., LTD. (JP) | 1981-12-29 | — | — | US | disclosed |