Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | MMP13 | P45452 | 2/20 | 0.57 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.53 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30098939 | 0.86 | MMP13 (0.59) | NPC1RAB9AMMP13GPR139SMN1; SMN2 | |
| SCHEMBL30098920 | 0.86 | MMP13 (0.59) | NPC1RAB9AMMP13GPR139SMN1; SMN2 | |
| SCHEMBL1769592 | 0.85 | NPC1 (0.57) | NPC1RAB9AMMP13GPR139SMN1; SMN2 | |
| SCHEMBL1769588 | 0.85 | NPC1 (0.57) | NPC1RAB9AMMP13GPR139SMN1; SMN2 | |
| SCHEMBL30098900 | 0.82 | ALDH1A1 (0.58) | NPC1RAB9AMMP13GPR139SMN1; SMN2 | |
| SCHEMBL5672356 | 0.80 | HPGD (0.72) | NPC1RAB9AMMP13GPR139SMN1; SMN2 | |
| SCHEMBL30099051 | 0.80 | MMP13 (0.56) | NPC1RAB9AMMP13GPR139SMN1; SMN2 | |
| SCHEMBL47353 | 0.79 | MMP13 (0.66) | NPC1RAB9AMMP13SMN1; SMN2GAA | |
| SCHEMBL5869864 | 0.79 | CTSL (0.53) | NPC1RAB9AMMP13GPR139SMN1; SMN2 | |
| SCHEMBL5869856 | 0.79 | CTSL (0.53) | NPC1RAB9AMMP13GPR139SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |