Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.60 |
| ▸ | CA1 | P00915 | 3/20 | 0.60 |
| ▸ | GRN | P28799 | 3/20 | 0.57 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 7/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | F3 | P13726 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830491 | 1.00 | CA2 (0.60) | CA2CA1GRNSORT1CA12 | |
| SCHEMBL9831508 | 0.85 | CA2 (0.51) | CA2CA1CA12CA9ALDH1A1 | |
| SCHEMBL9831504 | 0.85 | CA2 (0.51) | CA2CA1CA12CA9ALDH1A1 | |
| SCHEMBL24283516 | 0.83 | GRN (0.74) | CA2CA1GRNSORT1CTSL | |
| SCHEMBL24283517 | 0.83 | GRN (0.74) | CA2CA1GRNSORT1CTSL | |
| SCHEMBL4794969 | 0.81 | CTSL (0.71) | CA2CA1GRNSORT1CTSL | |
| SCHEMBL4159712 | 0.81 | CTSL (0.71) | CA2CA1GRNSORT1CTSL | |
| SCHEMBL2158906 | 0.80 | CTSL (0.67) | CA2CA1GRNSORT1CA12 | |
| SCHEMBL4465251 | 0.80 | CTSL (0.67) | CA2CA1GRNSORT1CA12 | |
| SCHEMBL2158900 | 0.80 | CTSL (0.67) | CA2CA1GRNSORT1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |