Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829477 | 0.82 | DHFR (0.63) | DHFR | |
| SCHEMBL380792 | 0.79 | DHFR (0.67) | DHFR | |
| Hydrochloric Acid SCHEMBL8377343 | 0.78 | DHFR (0.65) | DHFR | |
| Water SCHEMBL28837029 | 0.78 | DHFR (0.65) | DHFR | |
| SCHEMBL3646094 | 0.75 | — | — | |
| SCHEMBL6933468 | 0.74 | PDGFRB (0.53) | — | |
| SCHEMBL8902491 | 0.73 | DHFR (0.68) | DHFR | |
| SCHEMBL5742994 | 0.72 | CYP1A2 (0.52) | — | |
| SCHEMBL263918 | 0.72 | CYP1A2 (0.52) | — | |
| SCHEMBL30101236 | 0.72 | CYP1A2 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0096214-B1 | ANTIBACTERIAL PYRIMIDINE COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-02-27 | — | — | EP | disclosed |
| US-4587341-A | BACTERICIDES | BURROUGHS WELLCOME CO. (US) | 1986-05-06 | — | — | US | disclosed |
| EP-0096214-A1 | Antibacterial pyrimidine compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1983-12-21 | — | — | EP | disclosed |