Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830769 | 0.82 | HSD11B1 (0.53) | HSD11B1 | |
| SCHEMBL9831021 | 0.81 | HSD11B1 (0.42) | HSD11B1NPC1RAB9ANR1H2NR1H3 | |
| SCHEMBL10941820 | 0.72 | NPC1 (0.49) | HSD11B1NPC1RAB9ANR1H2NR1H3 | |
| SCHEMBL17207294 | 0.71 | PRKD3 (0.36) | GRM5MAPK14PDE10AKDM4EMEN1 | |
| SCHEMBL9829408 | 0.71 | HSD11B1 (0.67) | HSD11B1 | |
| SCHEMBL9830639 | 0.71 | HSD11B1 (0.67) | HSD11B1NR1H2NR1H3 | |
| SCHEMBL9829855 | 0.70 | HSD11B1 (0.53) | HSD11B1 | |
| SCHEMBL9830811 | 0.68 | HSD11B1 (0.48) | HSD11B1 | |
| SCHEMBL24407519 | 0.68 | GAA (0.40) | HSD11B1GRM5MAPK14P2RX7PDE10A | |
| SCHEMBL9829686 | 0.67 | HSD11B1 (0.50) | HSD11B1NPC1RAB9ANR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185256-B1 | TRIAZOLE DERIVATES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | CIBA-GEIGY AG (CH) | 1991-01-30 | — | — | EP | claimed |