Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4552092 | 0.80 | ERCC5 (0.46) | ERCC5FEN1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11718733 | 0.78 | HPGD (0.44) | ERCC5FEN1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16714061 | 0.73 | HPGD (0.46) | ERCC5FEN1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9830781 | 0.72 | ERCC5 (0.41) | ERCC5FEN1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1878466 | 0.71 | SLC6A2 (0.48) | ERCC5FEN1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL819137 | 0.71 | HPGD (0.47) | ERCC5FEN1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1685076 | 0.70 | HPGD (0.46) | ERCC5FEN1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28570713 | 0.70 | HPGD (0.46) | ERCC5FEN1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2233660 | 0.69 | HPGD (0.48) | ERCC5FEN1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL387303 | 0.69 | LMNA (0.57) | ERCC5FEN1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |