Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.54 |
| ▸ | CTSS | P25774 | 4/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KLK1 | P06870 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CTSB | P07858 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830841 | 1.00 | CTSL (0.54) | CTSLCTSSATMCTRB1ALDH1A1 | |
| SCHEMBL16587917 | 1.00 | CTSL (0.54) | CTSLCTSSATMCTRB1ALDH1A1 | |
| SCHEMBL12069024 | 0.89 | TRPM8 (0.58) | CTSLCTSSATMCTRB1ALDH1A1 | |
| SCHEMBL8150285 | 0.89 | TRPM8 (0.58) | CTSLCTSSATMCTRB1ALDH1A1 | |
| SCHEMBL29161404 | 0.88 | ATM (0.65) | CTSLCTSSATMALDH1A1CYP3A4 | |
| SCHEMBL7886288 | 0.88 | CTRB1 (0.60) | CTSLCTSSATMCTRB1LMNA | |
| SCHEMBL20529450 | 0.88 | CTRB1 (0.60) | CTSLCTSSATMCTRB1LMNA | |
| SCHEMBL29467644 | 0.88 | CTRB1 (0.60) | CTSLCTSSATMCTRB1LMNA | |
| SCHEMBL7451788 | 0.87 | ATM (0.54) | CTSLCTSSATMCTRB1ALDH1A1 | |
| SCHEMBL19625531 | 0.86 | KLK1 (0.49) | CTSLCTSSATMCTRB1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |