Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 9/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5857603 | 0.98 | CA2 (0.55) | CA2CA1FOLH1TDP1LMNA | |
| SCHEMBL5855561 | 0.94 | CA2 (0.56) | CA2CA1FOLH1TDP1LMNA | |
| SCHEMBL16149959 | 0.94 | CA2 (0.56) | CA2CA1FOLH1TDP1LMNA | |
| SCHEMBL16155818 | 0.94 | CA2 (0.56) | CA2CA1FOLH1TDP1LMNA | |
| SCHEMBL715646 | 0.87 | CA2 (0.67) | CA2CA1FOLH1TDP1LMNA | |
| SCHEMBL698067 | 0.87 | CA2 (0.67) | CA2CA1FOLH1TDP1LMNA | |
| SCHEMBL97498 | 0.87 | CA2 (0.67) | CA2CA1FOLH1TDP1LMNA | |
| SCHEMBL5856865 | 0.87 | LMNA (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4618531 | 0.86 | CA2 (0.65) | CA2CA1FOLH1TDP1LMNA | |
| Ammonia Solution, Strong SCHEMBL28375957 | 0.86 | CA2 (0.65) | CA2CA1FOLH1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |