Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | REN | P00797 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13091216 | 0.82 | TSHR (0.66) | TSHRNPSR1ALDH1A1THRBCYP2C19 | |
| SCHEMBL9830281 | 0.77 | ALDH1A1 (0.43) | TSHRNPSR1ALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL9832981 | 0.77 | HTT (0.49) | TSHRALDH1A1THRBMEN1KMT2A | |
| SCHEMBL13091164 | 0.73 | TSHR (0.69) | TSHRNPSR1ALDH1A1THRBCYP2C19 | |
| SCHEMBL9787250 | 0.73 | TSHR (0.38) | TSHRNPSR1ALDH1A1THRBCYP2C19 | |
| SCHEMBL10129665 | 0.72 | KMT2A (0.47) | TSHRMEN1KMT2A | |
| SCHEMBL10129676 | 0.72 | KMT2A (0.47) | TSHRMEN1KMT2A | |
| SCHEMBL10504486 | 0.71 | TSHR (0.41) | TSHRNPSR1ALDH1A1THRB | |
| SCHEMBL13090774 | 0.70 | TSHR (0.64) | TSHRNPSR1ALDH1A1THRBCYP2C19 | |
| SCHEMBL24022881 | 0.70 | ALOX15 (0.54) | TSHRNPSR1ALDH1A1THRBCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4729784-A | 1-(1,4-benzoxazin-3-on-6-yl)-dialkylmaleimides and use as herbicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1988-03-08 | — | — | US | claimed |
| EP-0255601-B1 | DIALKYLNALEINIMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDE | NIHON BAYER AGROCHEM K.K. (JP) | 1991-09-11 | — | — | EP | disclosed |
| US-4729784-A | 1-(1,4-benzoxazin-3-on-6-yl)-dialkylmaleimides and use as herbicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1988-03-08 | — | — | US | disclosed |
| EP-0255601-A2 | Dialkylnaleinimides, process for their preparation and their use as herbicide | NIHON BAYER AGROCHEM K.K. (JP) | 1988-02-10 | — | — | EP | disclosed |