Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15912310 | 0.82 | HCAR2 (0.53) | HCAR2HTTOPRM1CTSKLPAR1 | |
| SCHEMBL10125211 | 0.82 | HCAR2 (0.53) | HCAR2HTTOPRM1CTSKLPAR1 | |
| SCHEMBL10125207 | 0.82 | HCAR2 (0.53) | HCAR2HTTOPRM1CTSKLPAR1 | |
| SCHEMBL9829305 | 0.79 | HCAR2 (0.50) | HCAR2HTTOPRM1CTSKLPAR1 | |
| SCHEMBL9829311 | 0.79 | HCAR2 (0.50) | HCAR2HTTOPRM1CTSKLPAR1 | |
| SCHEMBL345954 | 0.78 | CTSK (0.46) | HCAR2HTTOPRM1CTSKLPAR1 | |
| SCHEMBL9830861 | 0.77 | CTSK (0.48) | HCAR2HTTOPRM1CTSKLPAR1 | |
| SCHEMBL9830863 | 0.77 | CTSK (0.48) | HCAR2HTTOPRM1CTSKLPAR1 | |
| SCHEMBL345120 | 0.77 | CTSK (0.46) | HCAR2HTTOPRM1CTSKLPAR1 | |
| SCHEMBL10152007 | 0.76 | HCAR2 (0.54) | HCAR2HTTOPRM1LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |