SCHEMBL9831030

SCHEMBL9831030

CONC(=O)C1C[CH]CN1C(C)=N

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 1/20 0.33
MMP2 P08253 1/20 0.30
ANPEP P15144 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9830180 0.78
SCHEMBL17966453 0.68 MMP2 (0.49) MMP2ANPEP
SCHEMBL9987703 0.65 TSHR (0.42) MMP2ANPEP
SCHEMBL15432291 0.60 MMP2 (0.41) MMP2ANPEP
SCHEMBL18231593 0.59 MMP1 (0.36) MMP2ANPEP
SCHEMBL18675302 0.58 DPP4 (0.51)
SCHEMBL17966454 0.58 ATM (0.31)
SCHEMBL2646433 0.58 CYP3A4 (0.49) GABRR1
SCHEMBL8111091 0.58 CYP3A4 (0.49) GABRR1
SCHEMBL13403377 0.57 SMN1; SMN2 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0226304-B1 COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC SANKYO COMPANY LIMITED (JP) 1991-08-28 EP claimed
US-4757066-A Reduces renal toxicity SANKYO COMPANY LIMITED (JP) 1988-07-12 US claimed
EP-0226304-A1 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1987-06-24 EP claimed
EP-0226304-B1 COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC SANKYO COMPANY LIMITED (JP) 1991-08-28 EP disclosed
US-4757066-A Reduces renal toxicity SANKYO COMPANY LIMITED (JP) 1988-07-12 US disclosed
EP-0226304-A1 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1987-06-24 EP disclosed