Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 8/20 | 0.60 |
| ▸ | METAP2 | P50579 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9698131 | 0.82 | REN (0.52) | RENMETAP2ALDH1A1KMT2AMETAP1 | |
| SCHEMBL9831355 | 0.82 | REN (0.53) | RENMETAP2METAP1 | |
| SCHEMBL10611167 | 0.80 | REN (0.49) | RENMETAP2ALDH1A1KMT2AMETAP1 | |
| SCHEMBL7290532 | 0.80 | REN (0.49) | RENMETAP2ALDH1A1KMT2AMETAP1 | |
| SCHEMBL9831906 | 0.76 | CTSS (0.43) | REN | |
| SCHEMBL7288187 | 0.74 | REN (0.56) | RENMETAP2ALDH1A1KMT2A | |
| SCHEMBL14420308 | 0.74 | REN (0.44) | RENMETAP2ALDH1A1KMT2AMETAP1 | |
| SCHEMBL14415383 | 0.74 | REN (0.44) | RENMETAP2ALDH1A1KMT2AMETAP1 | |
| SCHEMBL10611293 | 0.74 | REN (0.53) | RENMETAP2ALDH1A1KMT2AMETAP1 | |
| SCHEMBL628815 | 0.73 | CYP1A2 (0.44) | RENALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258289-A4 | PEPTIDE ANALOGS | — | 1991-01-02 | — | — | EP | disclosed |
| US-4857507-A | HYPOTENSIVE AGENT | ABBOTT LABORATORIES (US) | 1989-08-15 | — | — | US | disclosed |
| EP-0258289-A1 | PEPTIDE ANALOGS | ABBOTT LABORATORIES (US) | 1988-03-09 | — | — | EP | disclosed |
| WO-1987004349-A1 | PEPTIDE ANALOGS | DELLARIA JOSEPH | 1987-07-30 | — | — | WO | disclosed |