Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3202235 | 0.89 | ATM (0.56) | CTSKCTSLELANECASP3ATM | |
| SCHEMBL19859590 | 0.89 | ATM (0.56) | CTSKCTSLELANECASP3ATM | |
| SCHEMBL9749127 | 0.89 | ATM (0.56) | CTSKCTSLELANECASP3ATM | |
| SCHEMBL8604954 | 0.80 | CTSL (0.51) | CTSKCTSLTGM2ELANEATM | |
| SCHEMBL20467672 | 0.80 | TPSAB1 (0.53) | CTSKCTSLTGM2ATMTPSAB1 | |
| SCHEMBL31264459 | 0.79 | CTSL (0.56) | CTSKCTSLELANECASP3ATM | |
| SCHEMBL15395673 | 0.79 | ATM (0.54) | CTSKCTSLELANEATMTRPM8 | |
| SCHEMBL13202029 | 0.79 | CTSL (0.56) | CTSKCTSLELANECASP3ATM | |
| SCHEMBL6044753 | 0.78 | ELANE (0.51) | CTSKCTSLELANEATMCASP1 | |
| SCHEMBL6044757 | 0.78 | ELANE (0.51) | CTSKCTSLELANEATMCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |