Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.52 |
| ▸ | MPC2 | O95563 | 1/20 | 0.45 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10514710 | 0.83 | PPARG (0.51) | PPARGMPC2CYP2C8CYP2C9ALDH1A1 | |
| SCHEMBL9558560 | 0.83 | PPARG (0.49) | PPARGALDH1A1NPSR1MAPTPTPN1 | |
| SCHEMBL9830603 | 0.79 | FFAR1 (0.46) | PPARGALDH1A1NPSR1MAPTPTPN1 | |
| SCHEMBL377496 | 0.77 | FFAR1 (0.43) | PPARGMPC2CYP2C8CYP2C9ALDH1A1 | |
| SCHEMBL290976 | 0.77 | UTRN (0.48) | PPARGALDH1A1NPSR1MAPTFFAR1 | |
| SCHEMBL11640335 | 0.77 | GAA (0.58) | ALDH1A1 | |
| SCHEMBL9830775 | 0.76 | PPARG (0.43) | PPARGALDH1A1NPSR1MAPTPTPN1 | |
| SCHEMBL9832774 | 0.75 | ALDH1A1 (0.45) | PPARGALDH1A1NPSR1MAPTPTPN1 | |
| SCHEMBL9832866 | 0.75 | FFAR1 (0.57) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| SCHEMBL9832232 | 0.75 | FFAR1 (0.41) | PPARGALDH1A1NPSR1MAPTPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1026322-C | Process for preparing benzodumb azole derivatives | TANABE SEIYAKU CO (JP) | 1994-10-26 | — | — | CN | disclosed |
| EP-0283035-B1 | BENZOXAZOLE DERIVATIVES AND PREPARATION THEREOF | TANABE SEIYAKU CO., LTD. (JP) | 1991-11-06 | — | — | EP | disclosed |
| US-4948900-A | INTERMEDIATES FOR DIABETES THERAPEUTIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1990-08-14 | — | — | US | disclosed |
| US-4897393-A | ANTIDIABETIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1990-01-30 | — | — | US | disclosed |
| CN-88101542-A | Benzoxazole derivatives and process for preparing them | — | 1988-10-05 | — | — | CN | disclosed |
| EP-0283035-A1 | Benzoxazole derivatives and preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1988-09-21 | — | — | EP | disclosed |