Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 17/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | STK10 | O94804 | 1/20 | 0.39 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830541 | 0.87 | HSD11B1 (0.58) | HSD11B1TRPA1 | |
| SCHEMBL9830814 | 0.83 | HSD11B1 (0.54) | HSD11B1TRPA1 | |
| SCHEMBL9832170 | 0.83 | HSD11B1 (0.54) | HSD11B1TRPA1 | |
| SCHEMBL9829855 | 0.82 | HSD11B1 (0.53) | HSD11B1TRPA1 | |
| SCHEMBL9829823 | 0.81 | HSD11B1 (0.62) | HSD11B1TRPA1 | |
| SCHEMBL9832353 | 0.81 | HSD11B1 (0.51) | HSD11B1TRPA1 | |
| SCHEMBL9705543 | 0.81 | HSD11B1 (0.62) | HSD11B1TRPA1 | |
| SCHEMBL9831027 | 0.81 | HSD11B1 (0.50) | HSD11B1TRPA1 | |
| SCHEMBL9830599 | 0.80 | HSD11B1 (0.50) | HSD11B1TRPA1 | |
| SCHEMBL9829686 | 0.80 | HSD11B1 (0.50) | HSD11B1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180213779-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-08-02 | — | — | US | claimed |
| EP-3353160-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | Syngenta Participations AG (CH) | 2018-08-01 | — | — | EP | claimed |
| WO-2017050751-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-03-30 | — | — | WO | claimed |
| EP-3353160-B1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-03-04 | — | — | EP | disclosed |
| US-20180213779-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-08-02 | — | — | US | disclosed |
| EP-3353160-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | Syngenta Participations AG (CH) | 2018-08-01 | — | — | EP | disclosed |
| WO-2017050751-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-03-30 | — | — | WO | disclosed |
| EP-0185256-B1 | TRIAZOLE DERIVATES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | CIBA-GEIGY AG (CH) | 1991-01-30 | — | — | EP | disclosed |
| US-4788210-A | PESTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1988-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180213779-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | DDT, ACHE, GSTM1 | HSD11B1 359/4885P2RX7 1527/4885TRPA1 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.