Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 15/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 15/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 15/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9629549 | 0.79 | KDM4E (0.46) | ALDH1A1KDM4E | |
| SCHEMBL9823766 | 0.74 | TDP1 (0.46) | ADORA3ADORA2AADORA1ALDH1A1HSD17B10 | |
| SCHEMBL9313310 | 0.74 | ADORA3 (0.58) | ADORA3ADORA2AADORA1ALDH1A1ADORA2B | |
| SCHEMBL1256690 | 0.72 | MAPT (0.68) | ADORA2AADORA1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL9829889 | 0.71 | MAPT (0.58) | ADORA3ADORA2AADORA1ALDH1A1MAPT | |
| SCHEMBL22493221 | 0.71 | ADORA2A (0.76) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL11392444 | 0.71 | ADORA3 (0.56) | ADORA3ADORA2AADORA1ALDH1A1ADORA2B | |
| SCHEMBL18873089 | 0.70 | ADORA3 (0.48) | ADORA3ADORA2AADORA1ALDH1A1ADORA2B | |
| SCHEMBL570555 | 0.69 | ALDH1A1 (1.00) | ADORA3ADORA2AADORA1ALDH1A1MAPT | |
| SCHEMBL10054150 | 0.69 | KDM4E (0.64) | ALDH1A1HSD17B10MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321115-B1 | CARBOXAMIDE DERIVATIVES HAVING TETRAZOLE AND THIAZOLE RINGS AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4946855-A | ANTIALLERGIC | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0321115-A1 | Carboxamide derivatives having tetrazole and thiazole rings and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-21 | — | — | EP | disclosed |