Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.55 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.52 |
| ▸ | TACR1 | P25103 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830988 | 0.90 | MMP1 (0.56) | CAPN1 | |
| SCHEMBL9417356 | 0.87 | HDAC1 (0.56) | POLBHDAC1HDAC6ACEHDAC8 | |
| SCHEMBL8765767 | 0.83 | HDAC8 (0.58) | POLBTACR1HDAC8ALDH1A1KMT2A | |
| SCHEMBL7357746 | 0.82 | CAPN1 (0.53) | ACECAPN1 | |
| SCHEMBL10593105 | 0.82 | CAPN1 (0.53) | ACECAPN1 | |
| SCHEMBL8910575 | 0.82 | HDAC1 (0.53) | POLBHDAC1HDAC6CAPN1HDAC8 | |
| SCHEMBL28258931 | 0.81 | ACE (0.57) | POLBHDAC1HDAC6ACETACR1 | |
| SCHEMBL28258933 | 0.81 | ACE (0.57) | POLBHDAC1HDAC6ACETACR1 | |
| SCHEMBL8910628 | 0.81 | KMT2A (0.56) | POLBHDAC1HDAC6KMT2A | |
| SCHEMBL16063577 | 0.80 | ATM (0.53) | TACR1HDAC8KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258289-A4 | PEPTIDE ANALOGS | — | 1991-01-02 | — | — | EP | disclosed |
| EP-0258289-A1 | PEPTIDE ANALOGS | ABBOTT LABORATORIES (US) | 1988-03-09 | — | — | EP | disclosed |
| WO-1987004349-A1 | PEPTIDE ANALOGS | DELLARIA JOSEPH | 1987-07-30 | — | — | WO | disclosed |